The 450% thing is a myth. There WAS a bug a long time ago (1.07 or 1.08) that going over a certain MF% would make it to where no sets/uniques dropped, but that was patched.
yes i remember something like that... was long ago
what might be true is that after 650-700% mf the REAL uniq/set mf increases slightly compared to the global mf, like 700% is almost as good as 80000%