That's the thing about this vaccine. The M2e protein is conserved by a-strain influenza, so even the mutants would have that protein. Since the antibody specifically targets that protein it should fight off mutant strains as well. Of course if the mutant evolves and sheds itself of that protein a new vaccine would be needed it seems like.
Yeah, but I don't know nearly enough about that kind of thing to tell if it could survive without that protein. Biology really isn't my field, I'd have to ask my friend Bryan.
I know that the current flu vaccines get mixed reviews. For the elderly, it can be life-saving. Professionals generally recommend it for children also.
For otherwise healthy people, though, it has a tendency to cause long-lasting cold symptoms. One of my coworkers got one a few years back and was sick for several months. The next year, he skipped the vaccination and felt fine for the whole of "flu season."
Yeah, it would be nice if they could produce a reliable vaccine to deal with influenza once and for all, but given the track record, I'm not going to hold my breath.