Please help

Well, when you copid and pasted it from one directory to another, you fucked up the files. The registry and such were set to C:\

You never copy and paste a program to a new directory. Uniinstall and delete all RPG Maker folders(copy your project to the desktop) and then clean install everything to the D:\ drive adn then put your game in the projects folder.

When uninstalling, if it asks to remove any information, do so. If it asks to keep any information, don't.

So never copy and paste a program anywheres, even if its just up/down one folder. A computer can not comprehend it, it thinks things do not exist any more.

Also make sure to delete the old shortcuts and such.

This is the only way it can work again, learn from your mistakes man.