Yes, it would work. No, not effectively (for PvP), for most of the same reasons Zeal doesn't work well outside of Palapk.

Nobody is going to sit still while you Strafe them, attack rating bonuses/skills are hard to be found on an Amazon, and you're locked in place until your Strafe has finished. Not only does Guided Arrow track an enemy, it always hits (needing no AR bonuses), but you still get a decent framerate using it with a bit of IAS (unless you're using some pitiful bow).

A Strafe zon would be fodder for anything that teleports or has any FR/W.