A few that one of my friends has come up with:

- Oblivion (whihc you obviously know already)
- Mass Effect
- Blue Dragon
- Enchanted Arms

Blue Dragon is a three disc jobby, and seems to be in the cartoon anime style, but 3D. Enchanted Arms is somewhat pretty, but the battle system lacks somewhat. Both of these apparently have really annoying Japanese styles.

Mass Effect is a must-buy. No questions asked.

You could argue that Assassin's Creed has RPG elements to it, also. Either way, it's also a must-buy.