Not really, it all has to do w/ speed if Mario was fast enough he could doge the buster shots and that other shit. Don't you watch DBZ or play Smash Bros? It ALWAYS about the speed, if your quick enough it doesn't matter how powerful the enemy is, you can get the another way. But Mega Man would win, he can do so much more, and he has so many more attacks. Think off all the enemys skillz he's jacked. PWN